Risk factors for preterm births in lady reading hospital, Peshawar

To determine the various maternal and neonatal risk factors of preterm birth. A descriptive case series was conducted from 1st January 2010 to 3Jxt December 2010. In this study all cases, a live Pre term birth [PTB] [29 - <37 weeks] by vaginal delivery or caesarean section and their mothers were included. A total of 205 [04.04%] neonates were identified as premature neonates. Majority [29.3%] were in the age range of 2 days with mean age of 1.5073 +/- 1.2627 days. Out of 205, 51.7% were male and 48.3% were female. Maternal age of 21-35 years was recorded in majority 79.51% with mean age of 28.10 +/- 5.8982 years. Majority of mothers [96.1%] were illiterate, 76.6% belonged to rural areas, 76.1% belonged to poor class, 35.1% were multiparas. A history of Premature rupture of membrane [PROM] was found in 61% cases, history of burning micturition 4.9%, physical injuries 0.5%, polyhydramnios 14.14%, previous low birth weight baby 41.5%, threaten abortion 27.8%, antepartum hemorrhage 36.1%, previous perinatal loss 31.2%, previous premature birth 30.2%, maternal pyrexia 14.1%, previous twins 6.3% and placenta previa 4.4%. Frequency of prematurity was 04.04%. Among the various risk factors maternal age, illiteracy, rural residence, poverty, joint family setup, history of PROM, previous low birth weight babies, history of antepartum hemorrhage, multiparity, previous perinatal loss, previous premature babies, threaten abortion, were the prominent risk factors found in majority of cases

Frequency of various neonatal complications in infants born to diabetic mothers - a hospital base study

To determine the frequency of various complications occurring in infants of diabetic mothers. This descriptive study was conducted in the neonatal unit and obstetric units of Lady Reading Hospital, Peshawar from January to July 2010. Forty two consecutive cases of infants of diabetic mothers were enrolled in the study. Maternal history especially obstetric history and history regarding diabetes mellitus was obtained and complete neonatal examination was performed. The physical findings and anthropometric measurements were recorded into a printed Proforma. Serum glucose, serum calcium, hematocrit and echocardiography was performed in all enrolled babies. Out of 42 diabetic mothers, gestation diabetes was seen in 71.4% while pre-conceptional diabetes was seen in 28.5%. The male Infants of Diabetic Mothers in this study were 69%. Infant of Diabetic Mothers delivered by C-section were 45%. Macrosomia 40.4% [n=42] was found to be the most common complication followed by hypoglycaemia 23.8%. The mortality rate in our study was 4.7% [n=2]. This study confirms the high occurrence of complications in newborns, born to diabetic mothers. Large for gestational age and hypoglycemia were the commonest complications

Prevalence of rhesus type and abo incompatibility in jaundiced neonates

To determine the prevalence of Rh and ABO incompatibility in jaundiced neonates. This hospital based descriptive study was conducted in Pediatrics Unit, Lady Reading Hospital Peshawar. A total of 200 neonates with clinically diagnosed jaundice were included in the study. Out of 200 neonates 70% were male and 30%female. Majority of neonates 99.5% age was ranged from 0-10 days while only 0.5% neonate was 13 days. Out of 200 neonates, the frequency of ABO-incompatibility and Rh-incompatibility in jaundiced neonates in this study was 22.5% and 12.5% respectively. Out of the remaining 65.5% cases physiological jaundice was diagnosed in 40.5% neonates, prematurity in 15% neonates and G6PD in 9.5% neonates. Among 22.5% cases of ABO incompatibility there were 16.5% males and 6% females. Majority 15% presented on 1[st] day of life, followed by 3% on 2[nd] and 3[rd] day of life respectively, 1% on 4[th] day, 0.5% on 5[th] day of life. Out of 200 neonates presented with jaundice, prevalence of ABO-incompatibility was found to be 22.5% followed by Rh-incompatibility 12.5%

comparative study of measles complications in vaccinated versus non-vaccinated children

To find out and compare the frequency of measles complications among vaccinated and nonvaccinated children. This hospital based cross-sectional comparative study was conducted in Pediatrics Unit, PGMI/LRH, Peshawar All the patients were divided into two groups. In group 1, 100 vaccinated and in group 2, 100 non-vaccinated children were included. Both groups were compared for complications of measles. In group 1, majority [51%] cases were in age range of 1-3 years and in group 2, majority [59%] cases were also in age range of 1-3 years. In group 1, male were 55 [55%] and 45 [45%] were female. In group 2, male were 53 [53%] and 47 [47%] female. In group 1, complications include bronchopneumonia in 49 [49%], upper respiratory tract infection in 39 [39%], diarrhea in 32 [32%], oral ulcer in 31 [31%], dehydration in 15 [15%], otitis media in 10 [10%], malnutrition in 2 [2%], encephalitis in only 1 [1%] case. In group 2, bronchopneumonia in 51 [51%], diarrhea in 50 [50%], upper respiratory tract infection in 24 [24%], oral ulcer in 22 [22%], dehydration in 20 [20%], otitis media in 17 [17%], malnutrition in 12 [12%], and encephalitis in 11 [11%] patients. Nearly 50% of children in both groups were less than 5 years of age. This indicates that many children of this age group are still unprotected. Overall difference in vaccinated and unvaccinated groups was statistically significant [P value = 0.001]

Analysis of cervical smears in a Muslim population

Screening for cancer of the cervix remains a neglected health care issue in Pakistan. To provide baseline data for future efforts to improve screening, we conducted a retrospective analysis of cervical smears taken in the obstetrics and gynaecological clinics of the Aga Khan University Hospital, Karachi, Pakistan. Method: We collected data on cervical smear cytology for cervical smears taken from January 1, 1990 to December 31,1996. We assessed risk factors for dysplasia, including age, age at first marriage, and number of pregnancies. The overall prevalence of abnormal smears in our study was 0.5%. Of 20,995 cervical smears, 12,451 [59.3%] smears showed non-specific inflammation, 7302 [34.8%] were reported as normal, 809 [3.85%] showed monillial infection, 148 [0.71%] showed atypia, 105 [0.5%] had dysplastic cytology, and 52 [0.25%] samples were inadequate. The highest incidence of dysplastic smears was seen in the age group 35 to 44 years. Of 105 patients with dysplasia, 12 were pregnant, and all were asymptomatic, while in 93 non-pregnant women, 33 were symptomatic. The low prevalence of abnormal smears, compared with data from Western populations, could be due to the inherent bias of health awareness in the women who attended our hospital. The results of this study may serve as a baseline for future comparisons. A larger community-based study may establish the exact prevalence of malignant and premalignant lesions so as to plan for future screening